A newer class of topical glaucoma therapy, Rho kinase inhibitors, works to lower intraocular pressure in patients with glaucoma via a novel mechanism. In this podcast, Mitch Ibach, OD, FAAO, of Vance Thompson Vision in Sioux Falls, SD, and Jessica Steen, OD, FAAO, of the Nova Southeastern University College of Optometry in Fort Lauderdale, FL, will discuss the mechanism of action of these agents, along with data supporting their use within the broader range of topical glaucoma therapies.