Retina

CRU Cofounder John Gelles, OD, gives his first impressions on how the conference is going thus far in Napa, California.

Researchers developed eye drop formulations 17-mer and H105A, both containing a short peptide, to administer to mice in the form of a drop on the eye’s surface.

The Retina Institute of Illinois is led by 9 physicians who have been providing comprehensive eye care in Illinois for almost 25 years.

Researchers set out to determine the age groups for which a polygenic risk score would most effectively predict glaucomatous risk and help inform cost-effective methods for disease detection.

ENCELTO is the first and only FDA-approved treatment for MacTel.

The study examined changes in genes and proteins of the retinas of 9 strains of mice.

The study found that 17.4% of Medicare patients needed subspecialized procedures relative to 5.6% of surgeons practicing in rural areas between 2012 and 2022.

The agent class’s pleiotropic effects should keep optometrists vigilant.

MonacoPro, the next evolution of Monaco from Optos, retains the powerful ultra-widefield SLO and spectral domain imaging while adding additional key product features.

Toronto-based Cellview currently designs and manufactures highly performant diagnostic imaging instruments that leverage internal R&D expertise, according to a news release.

The Sentinel Camera aims to address critical gaps in retinal disease screening by offering a portable device that captures high-quality images that require no dilation of the eye.

The gel addresses necrotic retinal cell death in dry age-related macular degeneration and geographic atrophy without requiring injections.

Optical coherence tomography angiography (OCTA) was performed in all participants; the choroidal and retinal changes were examined and recorded.

Susvimo 100 mg/mL for intravitreal use via ocular implant is a refillable implant surgically inserted into the eye during a one-time, outpatient procedure, continuously delivering a customized formulation of ranibizumab over time.

DRSS results remained stable or improved with OKT-TKI, and the drug was well-tolerated in the study.

The 3-year, $4.8 million award comes from the NIH Venture Program Oculomics Initiatives.

Preclinical studies evaluating NPI-001 have found that it boosts the endogenous antioxidant glutathione, which stops chemically aggressive oxygen molecules from further damaging retinal cells, according to Nacuity Pharmaceuticals.

OCU400 demonstrated meaningful improvement of 2-line gain (10 letters on ETDRS chart) in low-luminance visual acuity (LLVA) in treated eyes when compared to untreated fellow eyes.

Results showed that at 6 months post-surgery, at least 1-, 2-, and 3-line gains in best-corrected distance were achieved in 97.1%, 68.6%, and 51.4% of operated eyes, respectively.

City Therapeutics will develop a novel RNAi clinical candidate toward a specific disease target for intravitreal administration.

The company's lead product candidate Duravyu (vorolanib intravitreal insert), f/k/a EYP-1901, is anticipating topline data from several clinical trials in 2026.

Nocturnal hypoxia could be a new additional modifiable risk factor for nAMD.

The application was refiled following a December 20, 2024, meeting between the US Food and Drug Administration (FDA) and Astellas.

A recent study evaluated both deep neural networks and aggregation functions to determine ways to improve schizophrenia detection.

The primary safety endpoint was carried out through the percentage of patients with shift from normal (at baseline) to abnormal in any electrocardiogram (ECG).

The potential gene therapy candidate is being evaluated for geographic atrophy.

The 98 patients included in the study were from a retina outpatient clinic and were using 0.3% ofloxacin eye drops as prophylaxis against infection.

The rationale was that commercial mydriatics administered during retinopathy of prematurity (ROP) screening have been associated with cardiorespiratory and gastrointestinal adverse events.

After reviewing information collected on a patient database, the team suggested telephone prompts for patients with mental health concerns, text message reminders, and online educational tools to improve uptake to increase eye screening attendance.